منابع مشابه
Apoptotic Pathways in Pemphigus
Pemphigus is a group of human autoimmune blistering diseases of the skin in which autoantibodies to desmosome cadherins induce loss of cell-cell adhesion (acantholysis). In addition to steric hindrance and activation of intracellular signaling, apoptosis has been suggested to contribute to the mechanism by which pathogenic IgG induces acantholysis. We review the current literature examining the...
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In the present study, two series of experiments have been made to investigate the role of the dermis in determining alternative pathways of differentiation in the epidermis. Previous work has shown that the scaly metatarsal epidermis of 12-day chicken embryos, when isolated in culture on a plasma clot or various other substrata, fails to develop normally and undergoes a characteristic sequence ...
متن کاملReview Mitochondrial apoptotic pathways
Apoptosis or programmed cell death (PCD) is a physiological process characteristic of pluricellular organisms leading to self-destruction of the cell. It is therefore involved in development, homeostasis and host defense. However, a significant difference has been shown between mammalian cell apoptosis and non-mammalian cell apoptosis: mitochondria are implicated only in the former. Execution o...
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Procaspase aggregation is mediated by the binding of adaptor molecules to protein interaction domains in the prodomains of some caspases. Two general types of interaction domains have been identified. Procas-pases-8 and-10 each contain two tandem death effector domains (DEDs), while procaspases-1,-2,-4,-5, and-9 Introduction contain caspase recruitment domains (CARDs). In each Nearly all physio...
متن کاملThe Modulation of Apoptotic Pathways by Gammaherpesviruses
Apoptosis or programmed cell death is a tightly regulated process fundamental for cellular development and elimination of damaged or infected cells during the maintenance of cellular homeostasis. It is also an important cellular defense mechanism against viral invasion. In many instances, abnormal regulation of apoptosis has been associated with a number of diseases, including cancer developmen...
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ژورنال
عنوان ژورنال: Experimental Dermatology
سال: 2005
ISSN: 0906-6705,1600-0625
DOI: 10.1111/j.1600-0625.2005.0355h.x